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The dynein cortical anchor Num1 activates dynein motility by relieving Pac1/LIS1-mediated inhibition
Cortically anchored dynein orients the spindle through interactions with astral microtubules. In budding yeast, dynein is offloaded to Num1 receptors from microtubule plus ends. Rather than walking toward minus ends, dynein remains associated with plus ends due in part to its association with Pac1/L...
Kaydedildi:
| Yayımlandı: | J Cell Biol |
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| Asıl Yazarlar: | , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
The Rockefeller University Press
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4621840/ https://ncbi.nlm.nih.gov/pubmed/26483554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201506119 |
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