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Chemical and molecular regulation of enzymes that detoxify carcinogens.

Inductions of detoxication (phase 2) enzymes, such as glutathione transferases and NAD(P)H:(quinone-acceptor) oxidoreductase, are a major mechanism for protecting animals and their cells against the toxic and neoplastic effects of carcinogens. These inductions result from enhanced transcription, and...

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Autors principals: Prestera, T, Holtzclaw, W D, Zhang, Y, Talalay, P
Format: Artigo
Idioma:Inglês
Publicat: 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC46217/
https://ncbi.nlm.nih.gov/pubmed/8385353
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