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Emergent Stem Cell Homeostasis in the C. elegans Germline Is Revealed by Hybrid Modeling

The establishment of homeostasis among cell growth, differentiation, and apoptosis is of key importance for organogenesis. Stem cells respond to temporally and spatially regulated signals by switching from mitotic proliferation to asymmetric cell division and differentiation. Executable computer mod...

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Détails bibliographiques
Publié dans:Biophys J
Auteurs principaux: Hall, Benjamin A., Piterman, Nir, Hajnal, Alex, Fisher, Jasmin
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621618/
https://ncbi.nlm.nih.gov/pubmed/26200879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2015.06.007
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