Markedly Elevated Carbamazepine-10,11-epoxide/Carbamazepine Ratio in a Fatal Carbamazepine Ingestion

Carbamazepine is a widely used anticonvulsant. Its metabolite, carbamazepine-10,11-epoxide, has been found to display similar anticonvulsant and neurotoxic properties. While the ratio of parent to metabolite concentration varies significantly, at therapeutic doses the epoxide concentration is genera...

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Bibliografiske detaljer
Udgivet i:Case Rep Med
Main Authors: Russell, Jason L., Spiller, Henry A., Baker, Daniel D.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2015
Fag:
Case Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621337/
https://ncbi.nlm.nih.gov/pubmed/26550016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/369707
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