Hemagglutinin-Neuraminidase Balance Influences the Virulence Phenotype of a Recombinant H5N3 Influenza A Virus Possessing a Polybasic HA(0) Cleavage Site

Although a polybasic HA(0) cleavage site is considered the dominant virulence determinant for highly pathogenic avian influenza (HPAI) H5 and H7 viruses, naturally occurring virus isolates possessing a polybasic HA(0) cleavage site have been identified that are low pathogenic in chickens. In this st...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:J Virol
Autores principales: Diederich, Sandra, Berhane, Yohannes, Embury-Hyatt, Carissa, Hisanaga, Tamiko, Handel, Katherine, Cottam-Birt, Colleen, Ranadheera, Charlene, Kobasa, Darwyn, Pasick, John
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
Materias:
Pathogenesis and Immunity
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621126/
https://ncbi.nlm.nih.gov/pubmed/26246579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01238-15
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares