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Bst2/Tetherin Is Induced in Neurons by Type I Interferon and Viral Infection but Is Dispensable for Protection against Neurotropic Viral Challenge

In permissive mouse central nervous system (CNS) neurons, measles virus (MV) spreads in the absence of hallmark viral budding or neuronal death, with transmission occurring efficiently and exclusively via the synapse. MV infection also initiates a robust type I interferon (IFN) response, resulting i...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Holmgren, Alicia M., Miller, Katelyn D., Cavanaugh, Sarah E., Rall, Glenn F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621123/
https://ncbi.nlm.nih.gov/pubmed/26311886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01745-15
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