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Neurotropic Arboviruses Induce Interferon Regulatory Factor 3-Mediated Neuronal Responses That Are Cytoprotective, Interferon Independent, and Inhibited by Western Equine Encephalitis Virus Capsid

Cell-intrinsic innate immune responses mediated by the transcription factor interferon regulatory factor 3 (IRF-3) are often vital for early pathogen control, and effective responses in neurons may be crucial to prevent the irreversible loss of these critical central nervous system cells after infec...

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Detalhes bibliográficos
Main Authors: Peltier, Daniel C., Lazear, Helen M., Farmer, Jocelyn R., Diamond, Michael S., Miller, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3554193/
https://ncbi.nlm.nih.gov/pubmed/23192868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02858-12
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