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Natural Products Induce a G Protein-Mediated Calcium Pathway Activating p53 in Cancer Cells

Paclitaxel, etoposide, vincristine and doxorubicin are examples of natural products being used as chemotherapeutics but with adverse side effects that limit their therapeutic window. Natural products derived from plants and having low toxicity, such as quercetin, resveratrol, epigallocatechin gallat...

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Bibliographic Details
Published in:Toxicol Appl Pharmacol
Main Authors: van Ginkel, Paul R., Yan, Michael B., Bhattacharya, Saswati, Polans, Arthur S., Kenealey, Jason D.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620942/
https://ncbi.nlm.nih.gov/pubmed/26341291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2015.08.016
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