Algal chloroplast produced camelid V(H)H antitoxins are capable of neutralizing botulinum neurotoxin

We have produced three antitoxins consisting of the variable domains of camelid heavy chain-only antibodies (V(H)H) by expressing the genes in the chloroplast of green algae. These antitoxins accumulate as soluble proteins capable of binding and neutralizing botulinum neurotoxin. Furthermore, they a...

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Bibliografiska uppgifter
I publikationen:Plant Biotechnol J
Huvudupphovsmän: Barrera, Daniel J., Rosenberg, Julian N., Chiu, Joanna G., Chang, Yung-Nien, Debatis, Michelle, Ngoi, Soo-Mun, Chang, John T., Shoemaker, Charles B., Oyler, George A., Mayfield, Stephen P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2014
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620920/
https://ncbi.nlm.nih.gov/pubmed/25229405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pbi.12244
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