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Drosophila TRPA1 isoforms detect UV light via photochemical production of H(2)O(2)

The transient receptor potential A1 (TRPA1) channel is an evolutionarily conserved detector of temperature and irritant chemicals. Here, we show that two specific isoforms of TRPA1 in Drosophila are H(2)O(2) sensitive and that they can detect strong UV light via sensing light-induced production of H...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Guntur, Ananya R., Gu, Pengyu, Takle, Kendra, Chen, Jingyi, Xiang, Yang, Yang, Chung-Hui
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620854/
https://ncbi.nlm.nih.gov/pubmed/26443856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1514862112
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