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Fluorescent Mimics of Cholesterol that Rapidly Bind Surfaces of Living Mammalian Cells

Mammalian cells acquire cholesterol, a critical membrane constituent, through multiple mechanisms. We synthesized mimics of cholesterol, fluorescent N-alkyl-3β-cholesterylamine-glutamic acids, that are rapidly incorporated into cellular plasma membranes compared with analogous cholesteryl amides, et...

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Publicado en:Chem Commun (Camb)
Main Authors: Hymel, David, Cai, Sutang, Sun, Qi, Henkhaus, Rebecca S., Perera, Chamani, Peterson, Blake R.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620717/
https://ncbi.nlm.nih.gov/pubmed/26287483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5cc06325f
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