NLK functions to maintain proliferation and stemness of NSCLC and is a target of metformin

OBJECTIVE: Nemo-like kinase (NLK) is an evolutionarily conserved serine/threonine kinase that regulates the activity of a wide range of signal transduction pathways. Metformin, an oral antidiabetic drug, is used for cancer prevention. However, the significance and underlying mechanism of NLK and met...

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Bibliographic Details
Published in:J Hematol Oncol
Main Authors: Suwei, Dong, Liang, Zeng, Zhimin, Liu, Ruilei, Li, Yingying, Zou, Zhen, Li, Chunlei, Ge, Zhangchao, Lai, Yuanbo, Xue, Jinyan, Yang, Gaofeng, Li, Xin, Song
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620602/
https://ncbi.nlm.nih.gov/pubmed/26503334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0203-8
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