NLK functions to maintain proliferation and stemness of NSCLC and is a target of metformin

OBJECTIVE: Nemo-like kinase (NLK) is an evolutionarily conserved serine/threonine kinase that regulates the activity of a wide range of signal transduction pathways. Metformin, an oral antidiabetic drug, is used for cancer prevention. However, the significance and underlying mechanism of NLK and met...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Hematol Oncol
Prif Awduron: Suwei, Dong, Liang, Zeng, Zhimin, Liu, Ruilei, Li, Yingying, Zou, Zhen, Li, Chunlei, Ge, Zhangchao, Lai, Yuanbo, Xue, Jinyan, Yang, Gaofeng, Li, Xin, Song
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2015
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620602/
https://ncbi.nlm.nih.gov/pubmed/26503334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0203-8
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