Astroglial β-Arrestin1-mediated Nuclear Signaling Regulates the Expansion of Neural Precursor Cells in Adult Hippocampus

Adult hippocampal neurogenesis is crucial for preserving normal brain function, but how it is regulated by niche cells is uncertain. Here we show that β-arrestin 1 (β-arr1) in dentate gyrus (DG) regulates neural precursor proliferation. β-arr1 knockout (KO) mice show reduced neural precursor prolife...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tao, Yezheng, Ma, Li, Liao, Zhaohui, Le, Qiumin, Yu, Jialing, Liu, Xing, Li, Haohong, Chen, Yuejun, Zheng, Ping, Yang, Zhengang, Ma, Lan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620451/
https://ncbi.nlm.nih.gov/pubmed/26500013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep15506
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