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Regulation of amygdalar PKA by β-arrestin-2/phosphodiesterase-4 complex is critical for fear conditioning

β-arrestins, key regulators of receptor signaling, are highly expressed in the central nervous system, but their roles in brain physiology are largely unknown. Here we show that β-arrestin-2 is critically involved in the formation of associative fear memory and amygdalar synaptic plasticity. In resp...

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Detalhes bibliográficos
Main Authors: Li, Yuting, Li, Haohong, Liu, Xing, Bao, Guobin, Tao, Yezheng, Wu, Ziyan, Xia, Peng, Wu, Chunfu, Li, Baoming, Ma, Lan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2799795/
https://ncbi.nlm.nih.gov/pubmed/19955404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906941106
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