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Amylose-Based Cationic Star Polymers for siRNA Delivery

A new siRNA delivery system using a cationic glyco-star polymer is described. Spermine-modified 8-arm amylose star polymer (with a degree of polymerization of approximately 60 per arm) was synthesized by chemoenzymatic methods. The cationic star polymer effectively bound to siRNA and formed spherica...

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Bibliographische Detailangaben
Veröffentlicht in:Biomed Res Int
Hauptverfasser: Nishimura, Tomoki, Umezaki, Kaori, Mukai, Sada-atsu, Sawada, Shin-ichi, Akiyoshi, Kazunari
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619918/
https://ncbi.nlm.nih.gov/pubmed/26539548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/962941
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