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Screening Nylon-3 Polymers, a New Class of Cationic Amphiphiles, for siRNA Delivery

[Image: see text] Amphiphilic nucleic acid carriers have attracted strong interest. Three groups of nylon-3 copolymers (poly-β-peptides) possessing different cationic/hydrophobic content were evaluated as siRNA delivery agents in this study. Their ability to condense siRNA was determined in SYBR Gol...

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Detalhes bibliográficos
Publicado no:Mol Pharm
Main Authors: Nadithe, Venkatareddy, Liu, Runhui, Killinger, Bryan A., Movassaghian, Sara, Kim, Na Hyung, Moszczynska, Anna B., Masters, Kristyn S., Gellman, Samuel H., Merkel, Olivia M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4319696/
https://ncbi.nlm.nih.gov/pubmed/25437915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp5004724
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