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An Exploration of the Universe of Polyglutamine Structures

Deposits of misfolded proteins in the human brain are associated with the development of many neurodegenerative diseases. Recent studies show that these proteins have common traits even at the monomer level. Among them, a polyglutamine region that is present in huntingtin is known to exhibit a corre...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Gómez-Sicilia, Àngel, Sikora, Mateusz, Cieplak, Marek, Carrión-Vázquez, Mariano
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619799/
https://ncbi.nlm.nih.gov/pubmed/26495838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004541
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