Novel Function of Lysine Methyltransferase G9a in the Regulation of Sox2 Protein Stability

G9a is a lysine methyltransferase (KMTase) for histone H3 lysine 9 that plays critical roles in a number of biological processes. Emerging evidence suggests that aberrant expression of G9a contributes to tumor metastasis and maintenance of a malignant phenotype in cancer by inducing epigenetic silen...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Lee, Jae-Young, Lee, Se-Hwan, Heo, Sun-Hee, Kim, Kwang-Soo, Kim, Changhoon, Kim, Dae-Kwan, Ko, Jeong-Jae, Park, Kyung-Soon
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619656/
https://ncbi.nlm.nih.gov/pubmed/26492085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141118
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