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Modulation of the Surface Proteome through Multiple Ubiquitylation Pathways in African Trypanosomes

Recently we identified multiple suramin-sensitivity genes with a genome wide screen in Trypanosoma brucei that includes the invariant surface glycoprotein ISG75, the adaptin-1 (AP-1) complex and two deubiquitylating enzymes (DUBs) orthologous to ScUbp15/HsHAUSP1 and pVHL-interacting DUB1 (type I), d...

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Publicat a:PLoS Pathog
Autors principals: Zoltner, Martin, Leung, Ka Fai, Alsford, Sam, Horn, David, Field, Mark C.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619645/
https://ncbi.nlm.nih.gov/pubmed/26492041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005236
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