Ecto-5’-Nucleotidase Overexpression Reduces Tumor Growth in a Xenograph Medulloblastoma Model

BACKGROUND: Ecto-5’-nucleotidase/CD73 (ecto-5’-NT) participates in extracellular ATP catabolism by converting adenosine monophosphate (AMP) into adenosine. This enzyme affects the progression and invasiveness of different tumors. Furthermore, the expression of ecto-5’-NT has also been suggested as a...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Cappellari, Angélica R., Pillat, Micheli M., Souza, Hellio D. N., Dietrich, Fabrícia, Oliveira, Francine H., Figueiró, Fabrício, Abujamra, Ana L., Roesler, Rafael, Lecka, Joanna, Sévigny, Jean, Battastini, Ana Maria O., Ulrich, Henning
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619639/
https://ncbi.nlm.nih.gov/pubmed/26491983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140996
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