Ecto-5’-Nucleotidase Overexpression Reduces Tumor Growth in a Xenograph Medulloblastoma Model

BACKGROUND: Ecto-5’-nucleotidase/CD73 (ecto-5’-NT) participates in extracellular ATP catabolism by converting adenosine monophosphate (AMP) into adenosine. This enzyme affects the progression and invasiveness of different tumors. Furthermore, the expression of ecto-5’-NT has also been suggested as a...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Cappellari, Angélica R., Pillat, Micheli M., Souza, Hellio D. N., Dietrich, Fabrícia, Oliveira, Francine H., Figueiró, Fabrício, Abujamra, Ana L., Roesler, Rafael, Lecka, Joanna, Sévigny, Jean, Battastini, Ana Maria O., Ulrich, Henning
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619639/
https://ncbi.nlm.nih.gov/pubmed/26491983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140996
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