Ecto-5’-Nucleotidase Overexpression Reduces Tumor Growth in a Xenograph Medulloblastoma Model

BACKGROUND: Ecto-5’-nucleotidase/CD73 (ecto-5’-NT) participates in extracellular ATP catabolism by converting adenosine monophosphate (AMP) into adenosine. This enzyme affects the progression and invasiveness of different tumors. Furthermore, the expression of ecto-5’-NT has also been suggested as a...

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Bibliographic Details
Published in:PLoS One
Main Authors: Cappellari, Angélica R., Pillat, Micheli M., Souza, Hellio D. N., Dietrich, Fabrícia, Oliveira, Francine H., Figueiró, Fabrício, Abujamra, Ana L., Roesler, Rafael, Lecka, Joanna, Sévigny, Jean, Battastini, Ana Maria O., Ulrich, Henning
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619639/
https://ncbi.nlm.nih.gov/pubmed/26491983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140996
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