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CD8(+) T Cells Mediate Female-Dominant IL-4 Production and Airway Inflammation in Allergic Asthma

The prevalence and severity of bronchial asthma are higher in females than in males after puberty. Although antigen-specific CD8(+) T cells play an important role in the development of asthma through their suppressive effect on cytokine production, the contribution of CD8(+) T cells to sex differenc...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Ito, Chihiro, Okuyama-Dobashi, Kaori, Miyasaka, Tomomitsu, Masuda, Chiaki, Sato, Miki, Kawano, Tasuku, Ohkawara, Yuichi, Kikuchi, Toshiaki, Takayanagi, Motoaki, Ohno, Isao
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619475/
https://ncbi.nlm.nih.gov/pubmed/26488300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140808
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