KIT exon 10 variant (c.1621 A > C) single nucleotide polymorphism as predictor of GIST patient outcome

BACKGROUND: Tumor genotype plays a crucial role in clinical management of GIST. Whether genetic polymorphism of KIT may influence GIST patient outcome is unclear. METHODS: We investigated the biological and clinical significance of the presence of KIT exon 10 variant (c.1621 A > C), KIT(L541), in...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Brahmi, Mehdi, Alberti, Laurent, Dufresne, Armelle, Ray-Coquard, Isabelle, Cassier, Philippe, Meeus, Pierre, Decouvelaere, Anne-Valérie, Ranchère-Vince, Dominique, Blay, Jean-Yves
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619434/
https://ncbi.nlm.nih.gov/pubmed/26498480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1817-5
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