DCIS in BRCA1 and BRCA2 mutation carriers: prevalence, phenotype, and expression of oncodrivers C-MET and HER3

BACKGROUND: Studies report conflicting evidence regarding the existence of a DCIS-associated premalignant pathway in BRCA mutation carriers. We aimed to examine the prevalence, phenotype, and expression of oncodrivers in pure DCIS (pDCIS) and invasive breast cancer with concurrent DCIS (IBC + DCIS)...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Transl Med
Auteurs principaux: Yang, Rachel L., Mick, Rosemarie, Lee, Kathreen, Graves, Holly L., Nathanson, Katherine L., Domchek, Susan M., Kelz, Rachel R., Zhang, Paul J., Czerniecki, Brian J.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619378/
https://ncbi.nlm.nih.gov/pubmed/26496879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-015-0698-3
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