Organ Preservation in Rectal Adenocarcinoma: a phase II randomized controlled trial evaluating 3-year disease-free survival in patients with locally advanced rectal cancer treated with chemoradiation plus induction or consolidation chemotherapy, and total mesorectal excision or nonoperative management

BACKGROUND: Treatment of patients with non-metastatic, locally advanced rectal cancer (LARC) includes pre-operative chemoradiation, total mesorectal excision (TME) and post-operative adjuvant chemotherapy. This trimodality treatment provides local tumor control in most patients; but almost one-third...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Smith, J. Joshua, Chow, Oliver S., Gollub, Marc J., Nash, Garrett M., Temple, Larissa K., Weiser, Martin R., Guillem, José G., Paty, Philip B., Avila, Karin, Garcia-Aguilar, Julio
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
Subjects:
Study Protocol
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619249/
https://ncbi.nlm.nih.gov/pubmed/26497495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1632-z
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