Neoadjuvant Chemotherapy First, Followed by Chemoradiation and Then Surgery, in the Management of Locally Advanced Rectal Cancer

BACKGROUND: Standard therapy for locally advanced rectal cancer (LARC) is pre-operative chemo-radiotherapy (CRT) and post-operative chemotherapy. We began offering FOLFOX (5FU, leucovorin and oxaliplatin) as initial treatment for patients with high-risk LARC to target micrometastases, while treating...

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Bibliografiske detaljer
Udgivet i:J Natl Compr Canc Netw
Main Authors: Cercek, Andrea, Goodman, Karyn A., Hajj, Carla, Weisberger, Emily, Segal, Neil H., Reidy-Lagunes, Diane L., Stadler1, Zsofia K., Wu, Abraham, Weiser, Martin R, Paty, Phillip B., Guillem, Jose G., Nash, Garrett M., Temple, Larissa K., Garcia-Aguilar, Julio, Saltz, Leonard B.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5612781/
https://ncbi.nlm.nih.gov/pubmed/24717570
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