Severe acute respiratory syndrome coronavirus E protein transports calcium ions and activates the NLRP3 inflammasome

Severe acute respiratory syndrome coronavirus (SARS-CoV) envelope (E) protein is a viroporin involved in virulence. E protein ion channel (IC) activity is specifically correlated with enhanced pulmonary damage, edema accumulation and death. IL-1β driven proinflammation is associated with those patho...

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Publicat a:Virology
Autors principals: Nieto-Torres, Jose L., Verdiá-Báguena, Carmina, Jimenez-Guardeño, Jose M., Regla-Nava, Jose A., Castaño-Rodriguez, Carlos, Fernandez-Delgado, Raul, Torres, Jaume, Aguilella, Vicente M., Enjuanes, Luis
Format: Artigo
Idioma:Inglês
Publicat: Elsevier Inc. 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619128/
https://ncbi.nlm.nih.gov/pubmed/26331680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.08.010
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