Severe Acute Respiratory Syndrome Coronavirus Envelope Protein Ion Channel Activity Promotes Virus Fitness and Pathogenesis

Deletion of Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) envelope (E) gene attenuates the virus. E gene encodes a small multifunctional protein that possesses ion channel (IC) activity, an important function in virus-host interaction. To test the contribution of E protein IC activity in...

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Autori principali: Nieto-Torres, Jose L., DeDiego, Marta L., Verdiá-Báguena, Carmina, Jimenez-Guardeño, Jose M., Regla-Nava, Jose A., Fernandez-Delgado, Raul, Castaño-Rodriguez, Carlos, Alcaraz, Antonio, Torres, Jaume, Aguilella, Vicente M., Enjuanes, Luis
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4006877/
https://ncbi.nlm.nih.gov/pubmed/24788150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004077
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