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Breaking Resistance of Pancreatic Cancer Cells to an Attenuated Vesicular Stomatitis Virus Through a Novel Activity of IKK inhibitor TPCA-1

Vesicular stomatitis virus (VSV) is an effective oncolytic virus against most human pancreatic ductal adenocarcinoma (PDAC) cell lines. However, some PDAC cell lines are highly resistant to oncolytic VSV-ΔM51 infection. To better understand the mechanism of resistance, we tested a panel of 16 small...

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Detalhes bibliográficos
Publicado no:Virology
Main Authors: Cataldi, Marcela, Shah, Nirav R., Felt, Sébastien A., Grdzelishvili, Valery Z.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619123/
https://ncbi.nlm.nih.gov/pubmed/26331681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.08.003
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