Hypermethylation of the FANCC and FANCL Promoter Regions in Sporadic Acute Leukaemia

Objective: Inactivation of the FA-BRCA pathway results in chromosomal instability. Fanconi anaemia (FA) patients have an inherited defect in this pathway and are strongly predisposed to the development of acute myeloid leukaemia (AML). Studies in sporadic cancers have shown promoter methylation of t...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Cell Oncol
Main Authors: Hess, C. J., Ameziane, N., Schuurhuis, G. J., Errami, A., Denkers, F., Kaspers, G. J. L., Cloos, J., Joenje, H., Reinhardt, D., Ossenkoppele, G. J., Zwaan, C. M., Waisfisz, Q.
Format: Artigo
Sprog:Inglês
Udgivet: IOS Press 2008
Fag:
Other
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618910/
https://ncbi.nlm.nih.gov/pubmed/18607065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/CLO-2008-0426
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker