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Hypermethylation of the FANCC and FANCL Promoter Regions in Sporadic Acute Leukaemia
Objective: Inactivation of the FA-BRCA pathway results in chromosomal instability. Fanconi anaemia (FA) patients have an inherited defect in this pathway and are strongly predisposed to the development of acute myeloid leukaemia (AML). Studies in sporadic cancers have shown promoter methylation of t...
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| Publicado no: | Cell Oncol |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
IOS Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4618910/ https://ncbi.nlm.nih.gov/pubmed/18607065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/CLO-2008-0426 |
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