Podocyte Regeneration Driven by Renal Progenitors Determines Glomerular Disease Remission and Can Be Pharmacologically Enhanced

Podocyte loss is a general mechanism of glomerular dysfunction that initiates and drives the progression of chronic kidney disease, which affects 10% of the world population. Here, we evaluate whether the regenerative response to podocyte injury influences chronic kidney disease outcome. In models o...

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Publicado en:Stem Cell Reports
Autores principales: Lasagni, Laura, Angelotti, Maria Lucia, Ronconi, Elisa, Lombardi, Duccio, Nardi, Sara, Peired, Anna, Becherucci, Francesca, Mazzinghi, Benedetta, Sisti, Alessandro, Romoli, Simone, Burger, Alexa, Schaefer, Beat, Buccoliero, Annamaria, Lazzeri, Elena, Romagnani, Paola
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier 2015
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618832/
https://ncbi.nlm.nih.gov/pubmed/26235895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.07.003
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