Notch Activation Differentially Regulates Renal Progenitors Proliferation and Differentiation Toward the Podocyte Lineage in Glomerular Disorders

Glomerular diseases account for 90% of end-stage kidney disease. Podocyte loss is a common determining factor for the progression toward glomerulosclerosis. Mature podocytes cannot proliferate, but recent evidence suggests that they can be replaced by renal progenitors localized within the Bowman�...

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Main Authors: Lasagni, Laura, Ballerini, Lara, Angelotti, Maria Lucia, Parente, Eliana, Sagrinati, Costanza, Mazzinghi, Benedetta, Peired, Anna, Ronconi, Elisa, Becherucci, Francesca, Bani, Daniele, Gacci, Mauro, Carini, Marco, Lazzeri, Elena, Romagnani, Paola
Formato: Artigo
Idioma:Inglês
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Tissue-Specific Stem Cells
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996085/
https://ncbi.nlm.nih.gov/pubmed/20680961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.492
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