Alpha-Synuclein Expression in the Oligodendrocyte Lineage: an In Vitro and In Vivo Study Using Rodent and Human Models

In this study, we sought evidence for alpha-synuclein (ASYN) expression in oligodendrocytes, as a possible endogenous source of ASYN to explain its presence in glial inclusions found in multiple system atrophy (MSA) and Parkinson’s disease (PD). We identified ASYN in oligodendrocyte lineage progenit...

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Veröffentlicht in:Stem Cell Reports
Hauptverfasser: Djelloul, Mehdi, Holmqvist, Staffan, Boza-Serrano, Antonio, Azevedo, Carla, Yeung, Maggie S., Goldwurm, Stefano, Frisén, Jonas, Deierborg, Tomas, Roybon, Laurent
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2015
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Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618831/
https://ncbi.nlm.nih.gov/pubmed/26235891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.07.002
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