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The spliceosome, a potential Achilles heel of MYC-driven tumors
Alterations in RNA splicing are frequent in human tumors. Two recent studies of lymphoma and breast cancer have identified components of the spliceosome — the core splicing machinery — that are essential for malignant transformation driven by the transcription factor MYC. These findings provide a di...
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| Опубликовано в: : | Genome Med |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4618744/ https://ncbi.nlm.nih.gov/pubmed/26490253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-015-0234-3 |
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