Activating Endogenous Neural Precursor Cells Using Metformin Leads to Neural Repair and Functional Recovery in a Model of Childhood Brain Injury

The development of cell replacement strategies to repair the injured brain has gained considerable attention, with a particular interest in mobilizing endogenous neural stem and progenitor cells (known as neural precursor cells [NPCs]) to promote brain repair. Recent work demonstrated metformin, a d...

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Detalhes bibliográficos
Publicado no:Stem Cell Reports
Main Authors: Dadwal, Parvati, Mahmud, Neemat, Sinai, Laleh, Azimi, Ashkan, Fatt, Michael, Wondisford, Fredric E., Miller, Freda D., Morshead, Cindi M.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618663/
https://ncbi.nlm.nih.gov/pubmed/26235894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.06.011
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