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Preferential Propagation of Competent SIX2+ Nephronic Progenitors by LIF/ROCKi Treatment of the Metanephric Mesenchyme

Understanding the mechanisms responsible for nephrogenic stem cell preservation and commitment is fundamental to harnessing the potential of the metanephric mesenchyme (MM) for nephron regeneration. Accordingly, we established a culture model that preferentially expands the MM SIX2+ progenitor pool...

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Bibliografski detalji
Izdano u:Stem Cell Reports
Glavni autori: Tanigawa, Shunsuke, Sharma, Nirmala, Hall, Michael D., Nishinakamura, Ryuichi, Perantoni, Alan O.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618653/
https://ncbi.nlm.nih.gov/pubmed/26321142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.07.015
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