Sall1 Maintains Nephron Progenitors and Nascent Nephrons by Acting as Both an Activator and a Repressor

The balanced self-renewal and differentiation of nephron progenitors are critical for kidney development and controlled, in part, by the transcription factor Six2, which antagonizes canonical Wnt signaling-mediated differentiation. A nuclear factor, Sall1, is expressed in Six2-positive progenitors a...

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Main Authors: Kanda, Shoichiro, Tanigawa, Shunsuke, Ohmori, Tomoko, Taguchi, Atsuhiro, Kudo, Kuniko, Suzuki, Yutaka, Sato, Yuki, Hino, Shinjiro, Sander, Maike, Perantoni, Alan O., Sugano, Sumio, Nakao, Mitsuyoshi, Nishinakamura, Ryuichi
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2014
Teme:
Basic Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4214521/
https://ncbi.nlm.nih.gov/pubmed/24744442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2013080896
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