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Preferential Propagation of Competent SIX2+ Nephronic Progenitors by LIF/ROCKi Treatment of the Metanephric Mesenchyme

Understanding the mechanisms responsible for nephrogenic stem cell preservation and commitment is fundamental to harnessing the potential of the metanephric mesenchyme (MM) for nephron regeneration. Accordingly, we established a culture model that preferentially expands the MM SIX2+ progenitor pool...

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Détails bibliographiques
Publié dans:Stem Cell Reports
Auteurs principaux: Tanigawa, Shunsuke, Sharma, Nirmala, Hall, Michael D., Nishinakamura, Ryuichi, Perantoni, Alan O.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618653/
https://ncbi.nlm.nih.gov/pubmed/26321142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.07.015
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