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Preferential Propagation of Competent SIX2+ Nephronic Progenitors by LIF/ROCKi Treatment of the Metanephric Mesenchyme

Understanding the mechanisms responsible for nephrogenic stem cell preservation and commitment is fundamental to harnessing the potential of the metanephric mesenchyme (MM) for nephron regeneration. Accordingly, we established a culture model that preferentially expands the MM SIX2+ progenitor pool...

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Bibliografiske detaljer
Udgivet i:Stem Cell Reports
Main Authors: Tanigawa, Shunsuke, Sharma, Nirmala, Hall, Michael D., Nishinakamura, Ryuichi, Perantoni, Alan O.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618653/
https://ncbi.nlm.nih.gov/pubmed/26321142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.07.015
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