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Randomized pharmacokinetic and drug–drug interaction studies of ceftazidime, avibactam, and metronidazole in healthy subjects

We assessed pharmacokinetic and safety profiles of ceftazidime–avibactam administered ± metronidazole, and whether drug–drug interactions exist between ceftazidime and avibactam, or ceftazidime-avibactam and metronidazole. The first study (NCT01430910) involved two cohorts of healthy subjects. Cohor...

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Bibliografiske detaljer
Udgivet i:Pharmacol Res Perspect
Main Authors: Das, Shampa, Li, Jianguo, Armstrong, Jon, Learoyd, Maria, Edeki, Timi
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618643/
https://ncbi.nlm.nih.gov/pubmed/26516584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.172
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