FTY720 (Fingolimod) sensitizes hepatocellular carcinoma cells to sorafenib-mediated cytotoxicity

Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related death worldwide. The multityrosine kinase inhibitor sorafenib is used in the therapy of advanced disease. However, the effects of sorafenib are limited, and combination treatments aiming at improved survival are encouraged...

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Bibliographic Details
Published in:Pharmacol Res Perspect
Main Authors: Ahmed, Dilruba, de Verdier, Petra J, Ryk, Charlotta, Lunqe, Oscar, Stål, Per, Flygare, Jenny
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2015
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618642/
https://ncbi.nlm.nih.gov/pubmed/26516583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.171
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