Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses

Multipotent human mesenchymal stromal cells (hMSCs) harbor immunomodulatory properties that are therapeutically relevant. One of the most clinically important populations of leukocytes is the interleukin-17A (IL-17A)-secreting T (Th17) lymphocytes. However, mechanisms of hMSC and Th17 cell interacti...

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Publicado no:Stem Cell Reports
Main Authors: Wang, Wei-Bei, Yen, Men-Luh, Liu, Ko-Jiunn, Hsu, Pei-Ju, Lin, Ming-Hong, Chen, Pei-Min, Sudhir, Putty-Reddy, Chen, Chein-Hung, Chen, Chung-Hsuan, Sytwu, Huei-Kang, Yen, B. Linju
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618596/
https://ncbi.nlm.nih.gov/pubmed/26321145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.07.013
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