Interleukin-25 Mediates Transcriptional Control of PD-L1 via STAT3 in Multipotent Human Mesenchymal Stromal Cells (hMSCs) to Suppress Th17 Responses

Multipotent human mesenchymal stromal cells (hMSCs) harbor immunomodulatory properties that are therapeutically relevant. One of the most clinically important populations of leukocytes is the interleukin-17A (IL-17A)-secreting T (Th17) lymphocytes. However, mechanisms of hMSC and Th17 cell interacti...

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Publicat a:Stem Cell Reports
Autors principals: Wang, Wei-Bei, Yen, Men-Luh, Liu, Ko-Jiunn, Hsu, Pei-Ju, Lin, Ming-Hong, Chen, Pei-Min, Sudhir, Putty-Reddy, Chen, Chein-Hung, Chen, Chung-Hsuan, Sytwu, Huei-Kang, Yen, B. Linju
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2015
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618596/
https://ncbi.nlm.nih.gov/pubmed/26321145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.07.013
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