Differential Notch and TGFβ Signaling in Primary Colorectal Tumors and Their Corresponding Metastases

Background: Loss of epithelial morphology and the acquisition of mesenchymal characteristics may contribute to metastasis formation during colorectal tumorigenesis. The Wnt, Notch and TGFβ signaling pathways control tissue homeostasis and tumor development in the gut. The relationship between the ac...

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Publicado no:Cell Oncol
Main Authors: Veenendaal, Liesbeth M., Kranenburg, Onno, Smakman, Niels, Klomp, Annemarie, Borel Rinkes, Inne H. M., van Diest, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: IOS Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618437/
https://ncbi.nlm.nih.gov/pubmed/18219106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2008/839076
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