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Integrative Genomics-Based Discovery of Novel Regulators of the Innate Antiviral Response
The RIG-I-like receptor (RLR) pathway is essential for detecting cytosolic viral RNA to trigger the production of type I interferons (IFNα/β) that initiate an innate antiviral response. Through systematic assessment of a wide variety of genomics data, we discovered 10 molecular signatures of known R...
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| Veröffentlicht in: | PLoS Comput Biol |
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| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4618338/ https://ncbi.nlm.nih.gov/pubmed/26485378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004553 |
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