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Integrative Analysis of the Acquisition of Pluripotency in PGCs Reveals the Mutually Exclusive Roles of Blimp-1 and AKT Signaling

Primordial germ cells (PGCs) are lineage-restricted unipotent cells that can dedifferentiate into pluripotent embryonic germ cells (EGCs). Here we performed whole-transcriptome analysis during the conversion of PGCs into EGCs, a process by which cells acquire pluripotency. To examine the molecular m...

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Publicat a:Stem Cell Reports
Autors principals: Nagamatsu, Go, Saito, Shigeru, Takubo, Keiyo, Suda, Toshio
Format: Artigo
Idioma:Inglês
Publicat: Elsevier 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618250/
https://ncbi.nlm.nih.gov/pubmed/26050930
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2015.05.007
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