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Telomerase Reverse Transcriptase Has an Extratelomeric Function in Somatic Cell Reprogramming

Reactivation of the endogenous telomerase reverse transcriptase (TERT) catalytic subunit and telomere elongation occur during the reprogramming of somatic cells to induced pluripotent stem (iPS) cells. However, the role of TERT in the reprogramming process is unclear. To clarify its function, the re...

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Autors principals: Kinoshita, Taisuke, Nagamatsu, Go, Saito, Shigeru, Takubo, Keiyo, Horimoto, Katsuhisa, Suda, Toshio
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140932/
https://ncbi.nlm.nih.gov/pubmed/24733392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.536037
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