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Telomerase Reverse Transcriptase Has an Extratelomeric Function in Somatic Cell Reprogramming

Reactivation of the endogenous telomerase reverse transcriptase (TERT) catalytic subunit and telomere elongation occur during the reprogramming of somatic cells to induced pluripotent stem (iPS) cells. However, the role of TERT in the reprogramming process is unclear. To clarify its function, the re...

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Detalhes bibliográficos
Main Authors: Kinoshita, Taisuke, Nagamatsu, Go, Saito, Shigeru, Takubo, Keiyo, Horimoto, Katsuhisa, Suda, Toshio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4140932/
https://ncbi.nlm.nih.gov/pubmed/24733392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.536037
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