ADAMTS1, CRABP1, and NR3C1 Identified as Epigenetically Deregulated Genes in Colorectal Tumorigenesis

Background: Gene silencing through CpG island hypermethylation is a major mechanism in cancer development. In the present study, we aimed to identify and validate novel target genes inactivated through promoter hypermethylation in colorectal tumor development. Methods: With the use of microarrays, t...

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Vydáno v:Cell Oncol
Hlavní autoři: Lind, Guro E., Kleivi, Kristine, Meling, Gunn I., Teixeira, Manuel R., Thiis-Evensen, Espen, Rognum, Torleiv O., Lothe, Ragnhild A.
Médium: Artigo
Jazyk:Inglês
Vydáno: IOS Press 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4618201/
https://ncbi.nlm.nih.gov/pubmed/17167179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2006/949506
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